Smallest transformation only appears to not reduce to H>>X transformation #58

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opened 2025-10-14 17:03:57 -06:00 by navan · 0 comments
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Originally created by @KramerChristian on 11/29/2019

The Smallest-transformation-only appears to not reduce single-cut transformations to H>>X transformations. For example, the transformation

[:1]c1ccccc1 >> [:1]c1ccc(F)cc1

is still in the database, although it could be reduced to

[:1][H] >> [:1]F

*Originally created by @KramerChristian on 11/29/2019* The Smallest-transformation-only appears to not reduce single-cut transformations to H>>X transformations. For example, the transformation [*:1]c1ccccc1 >> [*:1]c1ccc(F)cc1 is still in the database, although it could be reduced to [*:1][H] >> [*:1]F
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Reference: github/mmpdb#58
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